Multiple Myeloma: Current Knowledge and Future Perspectives

الملخص

Multiple Myeloma: Current Knowledge and Future Perspectives provides a comprehensive overview of multiple myeloma, a complex hematological malignancy characterized by the proliferation of monoclonal plasma cells. The book explores the disease’s epidemiology, pathophysiology, genetic abnormalities, clinical manifestations, diagnostic criteria, prognostic factors, and therapeutic strategies. Particular attention is given to renal impairment associated with multiple myeloma, including its mechanisms, histopathological features, prognosis, and management. The work also discusses advances in molecular biology, bone marrow microenvironment interactions, cytokine networks, and emerging targeted therapies such as proteasome inhibitors and monoclonal antibodies. By integrating current scientific evidence with clinical perspectives, this book highlights recent progress in diagnosis, personalized treatment, and patient monitoring, while emphasizing future research directions aimed at improving survival and quality of life for patients affected by multiple myeloma.