Protein Physiobiochemistry: Molecular, Cellular and Physiological Integration

Résumé

Protein Physiobiochemistry: Molecular Cellular and Physiological Integration is a pedagogical academic book devoted to proteins as essential biomolecules linking molecular chemistry, cellular biology and whole-organism physiology. It opens by defining protein physiobiochemistry and showing how proteins act as enzymes, structural elements, transporters, motors and signaling components. The text then builds from amino acids—their structure, chemical classification, essentiality and metabolic roles—to the hierarchical organization of proteins, including primary, secondary, tertiary and quaternary structures, folding units, stabilizing forces, allostery and protein dynamics. The middle chapters examine amino acid and protein metabolism through transamination, deamination, decarboxylation, the urea cycle, specialized amino acid pathways and links with carbohydrate and lipid metabolism. The book then moves to physiological functions, including energy homeostasis, muscle metabolism, plasma proteins, osmotic regulation and protein-related disorders such as malnutrition, amyloidosis and misfolding diseases. Later chapters explain translation, post-translational modifications, chaperone-assisted folding, protein targeting, trafficking, degradation, half-life regulation and cellular communication through receptors, kinases, phosphatases, adaptor proteins, GTPases and interaction networks. Written in a clear instructional tone, it is especially suited to students and readers in biochemistry, molecular biology, physiology, nutrition and biomedical sciences.